Molecularly Reversed Aging in Mice

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Researchers have discovered a cause of aging in mammals that may be reversible.

The essence of this finding is a series of molecular events that enable communication inside cells between the nucleus and mitochondria.

As communication breaks down, aging accelerates. By administering a molecule naturally produced by the human body, scientists restored the communication network in older mice. Subsequent tissue samples showed key biological hallmarks that were comparable to those of much younger animals.

nucleus-mito-Sinclair-Gomes

“The aging process we discovered is like a married couple—when they are young, they communicate well, but over time, living in close quarters for many years, communication breaks down,” said Harvard Medical School Professor of Genetics David Sinclair, senior author on the study.

“And just like with a couple, restoring communication solved the problem.”

Study author’s photo via The Australian.
Via Harvard Medical School.

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About Heretic

I design video games for a living, write fiction, political theory and poetry for personal amusement, and train regularly in Western European 16th century swordwork. On frequent occasion I have been known to hunt for and explore abandoned graveyards, train tunnels and other interesting places wherever I may find them, but there is absolutely no truth to the rumor that I am preparing to set off a zombie apocalypse. Nothing that will stand up in court, at least. I use paranthesis with distressing frequency, have a deep passion for history, anthropology and sociological theory, and really, really, really hate mayonnaise. But I wash my hands after the writing. Promise.

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